学校主页 联系我们 EN 　　
固定研究人员

王晓峰

联系电话：

Email：

研究领域

王晓峰

　　中文版本

　　1．基本信息

　　王晓峰，男，陕西咸阳人，西北农林科技大学旱区作物逆境生物学国家重点实验室研究人员，园艺学院教授、博士生导师。在西北农业大学园艺系学习，先后获学士和硕士学位，1993年7月留校任教。1999年在西北农业大学获博士学位。2000年至2002年在以色列农业研究中心（Volcani Center）和以色列魏兹曼研究所（Weizmann Institute）做博士后研究，2002年至2010年在美国北卡罗来纳州州立大学（NC State University）从事科研工作。

　　现为陕西省**特聘教授，陕西省政府特聘专家，陕西省园艺学会理事。

　　2．研究方向和研究兴趣

　　主要从事植物生化和分子生物学的研究及其在园艺作物代谢调控分子育种上的应用, 内容包括植物组织培养及遗传转化，基因克隆和功能分析，植物生长发育过程中的基因表达调控，植物激素信号传导的分子机制，植物信号传导的功能基因组学和蛋白组学等。研究兴趣主要为油菜素受体(BRI1) 及其相关受体(BAK1) 的互作组分及信号传导的分子机理， 膜蛋白受体的生物学功能和相互作用等，并致力于将这些基础研究的成果应用于园艺作物的栽培和育种实践。

　　3. 开设课程

　　主讲课程包括《园艺植物生物技术》、《英文植物科学进展》、《瓜果类蔬菜栽培学》、《新生研讨课》、《科研基本方法》、《蔬菜栽培学》、《蔬菜学研究进展》等。

　　4. 主要研究论文

  1. Yang Y, Liu J, Yin C, Vespoli LS, Ge D, Huang Y, Feng B, Xu G, Manhães AMEA, Dou S, Criswell C, Shan L, Wang X*, He P*.（2020） RNAi-based screen reveals concerted functions of MEKK2 and CRCK3 in plant cell death regulation. Plant Physiol. 183(1):331-344. doi: 10.1104/pp.19.01555. Epub 2020 Mar 12.

  2. Zhang S+, Li C+, Ren H, Zhao T, Li Q, Wang S, Zhang Y, Xiao F*, Wang X*（2020）BAK1 Mediates Light Intensity to Phosphorylate and Activate Catalases to Regulate Plant Growth and Development. International Journal of Molecular Sciences. 21(4) ii: E1437. doi: 10.3390/ijms21041437.

  3. Wang S.+, Liu J.+, Zhao T., Du C., Nie S., Zhang Y., Lv S., Huang S., Wang X*. (2019) Modification of Threonine-1050 of SlBRI1 regulates BR Signalling and increases fruit yield of tomato. BMC Plant Biol.19(1):256. doi: 10.1186/s12870-019-1869-9.

  4. Nie S , Huang S , Wang S , Mao Y , Liu J , Ma R , Wang X* . (2019) Enhanced brassinosteroid signaling intensity via SlBRI1 overexpression negatively regulates drought resistance in a manner opposite of that via exogenous BR application in tomato. Plant Physiol Biochem. 138:36-47. doi: 10.1016/j.plaphy.2019.02.014. Epub 2019 Feb 23.

  5. Zhang Y. +, Shuhua H.+, Wang X., Liu J., Guo X., Mu J, Tian J., Wang X*. (2018) Defective APETALA2 Genes Lead to Sepal Modification in Brassica Crops. Frontiers in Plant Science, 9, doi: 10.3389/fpls.2018.00367

  6. Imkampe J.+, Halter T.+, Huang S.+, Schulze S., Mazzotta S., Schmidt N., Manstretta R., Postel S., Wierzba M., Yang Y., vanDongen W.M., Stahl M., Zipfel C., Goshe M.B., Clouse S., de Vries S.C., Tax F., Wang X.*, Kemmerling B.* .(2017) The Arabidopsis Leucine-rich Repeat Receptor Kinase BIR3 Negatively Regulates BAK1 Receptor Complex Formation and Stabilizes BAK1. The Plant Cell. 29: 2285–2303.

  7. Huang S+, Nie S+, Wang S, Liu J, Zhang Y, Wang X*. (2017) SlBIR3 Negatively Regulates PAMP Responses and Cell Death in Tomato. International Journal of Molecular Sciences. 18(9). pii: E1966. doi: 10.3390/ijms18091966.

  8. Nie S+, Huang S+, Wang S, Cheng D, Liu J, Lv S, Li Q, Wang X*. （2017）Enhancing Brassinosteroid Signaling via Overexpression of Tomato (Solanum lycopersicum) SlBRI1 Improves Major Agronomic Traits. Frontiers in Plant Science. 8:0-1386. doi: 10.3389/fpls.2017.01386. eCollection 2017.

  9. Cheng Li+, Shan Zhang+, Xiaofeng Wang*. (2017) Novel Signaling Interface Constituted with Membrane Receptor-Like Kinases Emerged from the Study of Interaction and Transphosphorylation of BRI1 and BAK1. Current Topics in Medicinal Chemistry．17(21):2393-2400.

  10. Xin Wang, Dongli Gao, Jinjing Sun, Min Liu, YaoYao Lun, Jianshu Zheng, Shenhao Wang, Qingzhi Cui, Xiaofeng Wang*, Sanwen Huang*. (2016) An exon skipping in a SEPALLATA-Like gene is associated with perturbed floral and fruits development in cucumber. Journal of Integrative Plant Biology. 58（9）：766-771.

  11. Qiannan Wang+, Shufen Wang+, Sufu Gan, Xin Wang, Jianwei Liu, Xiaofeng Wang*. (2016) Role of Specific Phosphorylation Sites of Arabidopsis Brassinosteroid-Insensitive 1 Receptor Kinase in Plant Growth and Development. Journal of Plant Growth Regulation. 35(3): 755-769 .

  12. Shan Zhang+, Cheng Li+, Qi Li, Qiannan Wang, Shuhua Huang, Yanfeng Zhang and Xiaofeng Wang*. (2015)  Functional divergence of BAK1 Genes from Brassica rapa in regulating plant architecture. Genetics and Molecular Research. 14 (4): 14587-14596.

  13. Mitra SK, Chen R, Dhandayham M, Wang X, Blackburn RK, Kota U,Goshe MB, Schwarts D, Huber SC, Clouse SD*. (2015) An autophosphorylation site database for leucine-rich repeat receptor-like kinases in Arabidopsis thaliana. Plant Journal. 82(6):1042-60.

  14. Thierry Halter, Julia Imkampe, Sara Mazzotta, Michael Wierzba, Sandra Postel, Christoph Buecherl, Christian Kiefer, Mark Stahl, Delphine Chinchilla, Xiaofeng Wang, Thorsten Nuernberger, Cyril Zipfel, Steven Clouse, Jan Willem Borst, Sjef Boeren, Sacco C. de Vries, Frans Tax, Birgit Kemmerling. (2014) The Leucine-Rich Repeat Receptor Kinase BIR2 Is a Negative Regulator of BAK1 in Plant Immunity. Current Biology:24(2):134-143.

  15. Bajwa, Vikramjit S.; Wang, Xiaofeng; Blackburn, R. Kevin ; Goshe, Michael B.; Mitra, Srijeet K.; Williams, Elisabeth L.; Bishop, Gerard J.; Krasnyanski, Sergei; Allen, George; Huber, Steven C.; Clouse, Steven D. (2013) Identification and Functional Analysis of Tomato BRI1 and BAK1 Receptor Kinase Phosphorylation Sites. Plant Physiology: 163 (1): 30-42

  16. Man-Ho Oh, Xiaofeng Wang, Steven D. Clouse, and Steven C. Huber. (2012) Deactivation of the Arabidopsis BRI1 receptor kinase by autophosphorylation within the glycine-rich loop involved in ATP binding. Proc Natl Acad Sci U S A. 109(1):327-332.

  17. Man-Ho Oh, Xiaofeng Wang, Uma Kota, et al. (2009) Tyrosine phosphorylation of the BRI1 receptor kinase emerges as a component of Brassinosteroid signaling in Arabidopsis. Proc Natl Acad Sci U S A. 106 (2): 658-663

  18. Xiaofeng Wang, Uma Kota, Kai He, at al. (2008) Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in Brassinosteroid signaling. Developmental Cell 15(2):220-235

  19. Xiaofeng Wang, Michael B. Goshe, Erik J. et al. (2005) Identification and Functional Analysis of in vivo Phosphorylation Sites of the Arabidopsis BRASSINOSTEROID INSENSITIVE 1 Receptor Kinase. The Plant Cell，17(Jun): 1685–1703

      

　　5. 联系方式

　　通讯地址：陕西杨凌邰城路3号 西北农林科技大学园艺学院

　　邮编：712100

　　Email: wangxff99@nwsuaf.edu.cn; wangxf9993@yahoo.com

　　

　　English Vision

　　

　　Prof. Xiaofeng Wang, Ph. D.

　　State Key Laboratory of Crop Stress Biology in Arid Areas   

       College of Horticulture Northwest A&F University

       Yangling, Shaanxi, 712100 P. R. China E-mail: wangxff99@nwsuaf.edu.cn

　　

　　Education

　　07/1999    Ph.D., Plant Molecular Biology and Vegetable Physiology, Dissertation topic: Studies on genetic engineering of salt tolerance in Brassica Oleracea Var. Capitata and B . Napus .

　　07/1993    M.S., Crop Genetics and Breeding, Thesis: Genetic research of quantitative traits on oyster mushroom (Pleurotus Ostreatus).

　　07/1990  B.S., Horticulture,

　　All above degrees were earned in Northwestern University of Agriculture, P. R. China.

　　Professional Experience

　　2010--present   Professor, Associate Dean of College of Horticulture, Northwest A & F University, Shaanxi, P. R. China

　　2007--2010     Research Associate, North Carolina State University, NC, USA.

　　2002--2007     Post doctor, North Carolina State University, NC, USA.

　　2000--2002     Post doctor, Agricultural Research Organization of Israel (Volcani Center) and Weizmann Institute of Science, Israel

　　1999-2000     Associate Professor, Northwestern University of Agriculture, P. R. China

　　1993-1999    Assistant Professor, Northwestern University of Agriculture, P. R. China

　　Academic Interests

　　Brassinosteroids (BRs) are plant steroid hormones that regulate a wide range of developmental and physiological processes. I am interested in the signal transduction pathways through which BRs regulate plant growth and development. To gain a comprehensive understanding of the molecular mechanism of BRs signal transduction pathways and to provide inter-disciplinary training to students, a wide spectrum of approaches, including plant tissue culture,  genetic transformation, gene clones, molecular genetics, biochemistry, proteomics, and cell biology, have been applied. Furthermore, a large effort has been dedicated to molecular breedings of horticultural crops with the latest discoveries in molecular mechanism of BRs signal transduction pathway.

　　Courses Offered

　　The main courses have been taught: , < Cultivation Science of Vegetables> , < General Vegetable Gardening >, et al.

　　Honors and Awards

　　Honored with ‘Hundred of Excellent Experts in Shaanxi Province”

　　Selected Publications　　

  1. Yang Y, Liu J, Yin C, Vespoli LS, Ge D, Huang Y, Feng B, Xu G, Manhães AMEA, Dou S, Criswell C, Shan L, Wang X*, He P*.（2020） RNAi-based screen reveals concerted functions of MEKK2 and CRCK3 in plant cell death regulation. Plant Physiol. 183(1):331-344. doi: 10.1104/pp.19.01555. Epub 2020 Mar 12.

  2. Zhang S+, Li C+, Ren H, Zhao T, Li Q, Wang S, Zhang Y, Xiao F*, Wang X*（2020）BAK1 Mediates Light Intensity to Phosphorylate and Activate Catalases to Regulate Plant Growth and Development. International Journal of Molecular Sciences. 21(4) ii: E1437. doi: 10.3390/ijms21041437.

  3. Wang S.+, Liu J.+, Zhao T., Du C., Nie S., Zhang Y., Lv S., Huang S., Wang X*. (2019) Modification of Threonine-1050 of SlBRI1 regulates BR Signalling and increases fruit yield of tomato. BMC Plant Biol.19(1):256. doi: 10.1186/s12870-019-1869-9.

  4. Nie S , Huang S , Wang S , Mao Y , Liu J , Ma R , Wang X* . (2019) Enhanced brassinosteroid signaling intensity via SlBRI1 overexpression negatively regulates drought resistance in a manner opposite of that via exogenous BR application in tomato. Plant Physiol Biochem. 138:36-47. doi: 10.1016/j.plaphy.2019.02.014. Epub 2019 Feb 23.

  5. Zhang Y. +, Shuhua H.+, Wang X., Liu J., Guo X., Mu J, Tian J., Wang X*. (2018) Defective APETALA2 Genes Lead to Sepal Modification in Brassica Crops. Frontiers in Plant Science, 9, doi: 10.3389/fpls.2018.00367

  6. Imkampe J.+, Halter T.+, Huang S.+, Schulze S., Mazzotta S., Schmidt N., Manstretta R., Postel S., Wierzba M., Yang Y., vanDongen W.M., Stahl M., Zipfel C., Goshe M.B., Clouse S., de Vries S.C., Tax F., Wang X.*, Kemmerling B.* .(2017) The Arabidopsis Leucine-rich Repeat Receptor Kinase BIR3 Negatively Regulates BAK1 Receptor Complex Formation and Stabilizes BAK1. The Plant Cell. 29: 2285–2303.

  7. Huang S+, Nie S+, Wang S, Liu J, Zhang Y, Wang X*. (2017) SlBIR3 Negatively Regulates PAMP Responses and Cell Death in Tomato. International Journal of Molecular Sciences. 18(9). pii: E1966. doi: 10.3390/ijms18091966.

  8. Nie S+, Huang S+, Wang S, Cheng D, Liu J, Lv S, Li Q, Wang X*. （2017）Enhancing Brassinosteroid Signaling via Overexpression of Tomato (Solanum lycopersicum) SlBRI1 Improves Major Agronomic Traits. Frontiers in Plant Science. 8:0-1386. doi: 10.3389/fpls.2017.01386. eCollection 2017.

  9. Cheng Li+, Shan Zhang+, Xiaofeng Wang*. (2017) Novel Signaling Interface Constituted with Membrane Receptor-Like Kinases Emerged from the Study of Interaction and Transphosphorylation of BRI1 and BAK1. Current Topics in Medicinal Chemistry．17(21):2393-2400.

  10. Xin Wang, Dongli Gao, Jinjing Sun, Min Liu, YaoYao Lun, Jianshu Zheng, Shenhao Wang, Qingzhi Cui, Xiaofeng Wang*, Sanwen Huang*. (2016) An exon skipping in a SEPALLATA-Like gene is associated with perturbed floral and fruits development in cucumber. Journal of Integrative Plant Biology. 58（9）：766-771.

  11. Qiannan Wang+, Shufen Wang+, Sufu Gan, Xin Wang, Jianwei Liu, Xiaofeng Wang*. (2016) Role of Specific Phosphorylation Sites of Arabidopsis Brassinosteroid-Insensitive 1 Receptor Kinase in Plant Growth and Development. Journal of Plant Growth Regulation. 35(3): 755-769 .

  12. Shan Zhang+, Cheng Li+, Qi Li, Qiannan Wang, Shuhua Huang, Yanfeng Zhang and Xiaofeng Wang*. (2015)  Functional divergence of BAK1 Genes from Brassica rapa in regulating plant architecture. Genetics and Molecular Research. 14 (4): 14587-14596.

  13. Mitra SK, Chen R, Dhandayham M, Wang X, Blackburn RK, Kota U,Goshe MB, Schwarts D, Huber SC, Clouse SD*. (2015) An autophosphorylation site database for leucine-rich repeat receptor-like kinases in Arabidopsis thaliana. Plant Journal. 82(6):1042-60.

  14. Thierry Halter, Julia Imkampe, Sara Mazzotta, Michael Wierzba, Sandra Postel, Christoph Buecherl, Christian Kiefer, Mark Stahl, Delphine Chinchilla, Xiaofeng Wang, Thorsten Nuernberger, Cyril Zipfel, Steven Clouse, Jan Willem Borst, Sjef Boeren, Sacco C. de Vries, Frans Tax, Birgit Kemmerling. (2014) The Leucine-Rich Repeat Receptor Kinase BIR2 Is a Negative Regulator of BAK1 in Plant Immunity. Current Biology:24(2):134-143.

  15. Bajwa, Vikramjit S.; Wang, Xiaofeng; Blackburn, R. Kevin ; Goshe, Michael B.; Mitra, Srijeet K.; Williams, Elisabeth L.; Bishop, Gerard J.; Krasnyanski, Sergei; Allen, George; Huber, Steven C.; Clouse, Steven D. (2013) Identification and Functional Analysis of Tomato BRI1 and BAK1 Receptor Kinase Phosphorylation Sites. Plant Physiology: 163 (1): 30-42

  16. Man-Ho Oh, Xiaofeng Wang, Steven D. Clouse, and Steven C. Huber. (2012) Deactivation of the Arabidopsis BRI1 receptor kinase by autophosphorylation within the glycine-rich loop involved in ATP binding. Proc Natl Acad Sci U S A. 109(1):327-332.

  17. Man-Ho Oh, Xiaofeng Wang, Uma Kota, et al. (2009) Tyrosine phosphorylation of the BRI1 receptor kinase emerges as a component of Brassinosteroid signaling in Arabidopsis. Proc Natl Acad Sci U S A. 106 (2): 658-663

  18. Xiaofeng Wang, Uma Kota, Kai He, at al. (2008) Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in Brassinosteroid signaling. Developmental Cell 15(2):220-235

  19. Xiaofeng Wang, Michael B. Goshe, Erik J. et al. (2005) Identification and Functional Analysis of in vivo Phosphorylation Sites of the Arabidopsis BRASSINOSTEROID INSENSITIVE 1 Receptor Kinase. The Plant Cell，17(Jun): 1685–1703

　　Contact information

　　Address: #3 Taicheng Road, Northwest A&F University, College of Horticulture, Yangling, Shaanxi 712100, P. R. China

　　Email: wangxff99@nwsuaf.edu.cn; wangxf9993@yahoo.com